Blog entry by Joellen Rudolph
ADHD Medication During Pregnancy and Breastfeeding
The decision to stop or keep ADHD medications during pregnancy and nursing is a difficult decision for women suffering from the condition. There isn't much information on how long-term exposure to these medications can affect the fetus.
A recent study published in Molecular Psychiatry demonstrates that children exposed to ADHD medication during pregnancy do not develop neurological disorders like hearing loss or vision, febrile seizures, or IQ impairment. The authors acknowledge that further high-quality research is needed.
Risk/Benefit Analysis
Women who are pregnant and taking ADHD medications need to balance the benefits of taking them against the potential risks to the foetus. Doctors don't have enough data to provide clear recommendations, but can provide information on risks and benefits to aid pregnant women in making informed choices.
A study published in Molecular Psychiatry concluded that women who took ADHD medication in early pregnancy were not at greater risk of fetal malformations, or structural birth defects. The researchers used a large, population-based case-control study to determine the prevalence of major structural birth defects in infants born to mothers who had taken stimulants in early pregnancy, and those who did not. Pediatric cardiologists and clinical geneticists reviewed the cases to ensure an accurate case classification and to minimize the chance of bias.
However, the researchers' study was not without its flaws. In particular, they were unable to separate the effects of the medication from those of the disorder at hand. This makes it difficult for researchers to determine if the small differences observed between the groups exposed were due to medication use or affected by comorbidities. Additionally the researchers did not examine long-term offspring outcomes.
The study showed that infants whose mother had taken ADHD medication during pregnancy had a higher risk of admission to the neonatal care unit (NICU) in comparison to mothers who did not use any medication during pregnancy or discontinued taking their medication prior to or during pregnancy. The reason for this was central nervous system disorders. The increased risk of admission was not influenced by the stimulant medication that was used during pregnancy.
Women who took stimulant ADHD medications during pregnancy also had a higher likelihood of having an emergency caesarean section or having a baby that scored low on the Apgar scale (less than 7). These increases did appear to be unrelated to the type of medication taken during pregnancy.
The research suggests that the risk of a small amount with the use of ADHD medications during early pregnancy may be offset by the greater benefit to both mother and child of continuing treatment for the woman's disorder. Doctors should discuss with their patients about this issue and, if possible, help them improve coping skills which may reduce the effects of her disorder on her daily life and relationships.
Medication Interactions
As more women than ever before are being diagnosed with ADHD and being treated with medication, the question of whether or not to stop treatment during pregnancy is a question that more and more physicians confront. Often, these decisions are made without clear and authoritative evidence regardless, so doctors must weigh what they know from their own experiences, those of other doctors, and what research suggests on the subject and their best judgment for each individual patient.
The issue of risk to the infant can i get adhd meds without a diagnosis be particularly tricky. Many studies on this topic are based on observational data rather than controlled research, and their conclusions are often contradictory. In addition, most effective adhd medication for adults uk studies limit their analysis to live births, which could undervalue the serious teratogenic effects that can result in abortion or termination of the pregnancy. The study discussed in the journal club addresses these issues by analyzing the data from deceased and live births.
Conclusion A few studies have revealed a positive correlation between ADHD medications and certain birth defects however, other studies haven't established a link. The majority of studies show an unintended, or slightly negative, impact. In all cases, a careful evaluation of the potential risks and benefits must be performed.
It can be difficult, if not impossible for women with ADHD to stop taking their medication. In a recent article in Archives of Women's Mental Health by psychologist Jennifer Russell, she notes that stopping ADHD medications during pregnancy can increase depression and feelings of being isolated. Additionally, the loss of medication can affect the ability to perform jobs and drive safely that are crucial aspects of daily life for many people with ADHD.
She suggests that women who are not sure whether to take the medication or stop due to pregnancy educate family members, colleagues, and their friends about the condition, the effects on daily functioning, and the benefits of keeping the current treatment plan. It will also help a woman feel confident about her decision. It is important to remember that certain medications are able to pass through the placenta so if the patient decides to stop her ADHD medication during pregnancy and breastfeeding, she must be aware of the possibility that traces of the medication could be transferred to the child.
Risk of Birth Defects
As the use of ADHD medications to treat symptoms of attention deficit hyperactivity disorder (ADHD) grows, so do concerns about the effects that the drugs could have on foetuses. Recent research published in the journal Molecular Psychiatry has added to the body of knowledge regarding this issue. Using two massive data sets researchers were able to examine more than 4.3 million pregnancies and determine whether stimulant medication use increased the risk of birth defects. Although the risk overall remains low, the scientists found that exposure in the first trimester to ADHD medications was linked to a slightly higher rate of certain heart defects like ventriculo-septal defects (VSD).
The authors of the study found no association between early use of medication and congenital abnormalities such as facial clefting or club foot. The results are in the same vein as previous studies that showed the existence of a slight, but significant increase in the number of cardiac malformations among women who started taking ADHD medication prior to the time of the birth of their child. This risk increased during the latter half of pregnancy when many women decided to stop taking their medication.
Women who used ADHD medication in the first trimester of their pregnancies were also more likely to have a caesarean section, a low Apgar score after delivery and a baby who needed breathing assistance at birth. The authors of the study were not able to eliminate selection bias because they restricted the study to women without other medical conditions that could have contributed to the findings.
The researchers hope that their research will serve to inform the clinical decisions of physicians who treat pregnant women. The researchers advise that while discussing the risks and benefits are crucial, the decision on whether to continue or stop medication should be in light of the severity of each woman's Adhd medication Pregnancy symptoms and her requirements.
The authors warn that, while stopping the medication is an option to think about, it isn't advised due to the high rate depression and mental health issues in women who are expecting or who have recently given birth. Additionally, the research suggests that women who decide to stop taking their medications are more likely to experience difficulties getting used to life without them following the birth of their baby.
Nursing
The responsibilities of being a new mother can be overwhelming. Women suffering from ADHD may face a lot of challenges when they must manage their symptoms, attend doctor appointments and prepare for the birth of a baby and adjust to new routines. This is why many women choose to continue taking their ADHD medication throughout the pregnancy.
The majority of stimulant medications are absorbed through breast milk in very small quantities, so the risk to nursing infant is very low. The amount of exposure to medications can adhd medication help with memory vary depending upon the dosage the medication is administered, its frequency and the time of the day. In addition, individual medications enter the baby's system differently through the gastrointestinal tract as well as breast milk. The impact of this on a newborn infant is not well understood.
Due to the absence of research, some physicians might be tempted to stop taking stimulant drugs during a woman's pregnancy. This is a difficult decision for the patient, who must balance the benefits of keeping her medication against the possible risks to the foetus. As long as there is no more information, doctors should ask all pregnant patients about their experience with ADHD and if they are taking or planning to take medication during the perinatal period.
A growing number of studies have shown that the majority of women are able to safely continue taking their ADHD medication during pregnancy and while breastfeeding. In response, an increasing number of patients are opting to do so. They have found through consultation with their physicians, that the benefits of continuing their current medication outweigh any possible risks.
It's important for women with ADHD who are thinking of breastfeeding to seek a specialist psychiatrist's guidance prior to becoming pregnant. They should discuss their medication with their doctor as well as the pros and cons of continuing treatment. This includes non-pharmacological strategies. Psychoeducation is also required to help pregnant women suffering from ADHD recognize the signs and the underlying disorder. They should also learn about treatment options and reinforce the coping mechanisms. This should involve an approach that is multidisciplinary, including the GP as well as obstetricians, psychiatry and obstetricians. Pregnancy counseling should include a discussion of a treatment plan for the mother and the child, and monitoring for signs of deterioration and, if necessary, adjustments to the medication regime.